================================================================================ HAPSTAT Analysis ================================================================================ C:\hapstat\data\case-control.2.dat C:\hapstat\data\unrelated.dat ================================================================================ ================================================================================ Haplotype frequencies under Hardy-Weinberg equilibrium ================================================================================ Tolerance: 1e-006 Maximum iterations: 2000 Subjects: 2000 Cases: 1000 Controls: 1000 Unrelated: 1000 Haplotype Unrelated -------------------------- 00011 0.0058 00100 0.0053 00110 0.0000 01011 0.1392 01100 0.2453 01111 0.0024 10000 0.0106 10011 0.3329 10100 0.0645 10110 0.0385 11011 0.1401 11100 0.0123 11111 0.0032 -------------------------- Iterations 122 Log-Likelihood -2892.4686 -------------------------- Status: Success. ================================================================================ Additive haplotype effects under Hardy-Weinberg equilibrium ================================================================================ Tolerance: 0.0001 Maximum iterations: 500 Subjects: 1997/2000 Cases: 999/1000 Controls: 998/1000 Unrelated: 1000/1000 Estimate StdError Z-Stat P-Value ---------------------------------------------------------- Effects ---------------------------------------------------------- Gene 2 0 -0.2771 0.0573 -4.8320 0.0000 ---------------------------------------------------------- Frequencies ---------------------------------------------------------- 00011 0.0049 0.0011 4.3392 0.0000 00100 0.0045 0.0010 4.3239 0.0000 01011 0.1347 0.0050 26.8437 0.0000 01100 0.2655 0.0067 39.8577 0.0000 01111 0.0023 0.0012 1.8742 0.0609 10000 0.0101 0.0021 4.7714 0.0000 10011 0.3419 0.0069 49.2463 0.0000 10100 0.0574 0.0037 15.5574 0.0000 10110 0.0299 0.0022 13.4480 0.0000 11011 0.1362 0.0050 27.2077 0.0000 11100 0.0095 0.0016 5.9898 0.0000 11111 0.0030 0.0014 2.2315 0.0256 ---------------------------------------------------------- Iterations: 4 Log-Likelihood: -7905.9793 Status: Success. ==================== Report generated on 06/17/08 12:15:21 =====================