The SAS System            08:47 Monday, May 12, 2008   1

                                       The PHREG Procedure

                                        Model Information

                                Data Set                 WORK.A
                                Dependent Variable       time
                                Censoring Variable       delta
                                Censoring Value(s)       0
                                Ties Handling            BRESLOW


                             Number of Observations Read         312
                             Number of Observations Used         312


                       Summary of the Number of Event and Censored Values

                                                               Percent
                             Total       Event    Censored    Censored

                               312         125         187       59.94


                                       Convergence Status

                         Convergence criterion (GCONV=1E-8) satisfied.


                                      Model Fit Statistics

                                              Without           With
                             Criterion     Covariates     Covariates

                             -2 LOG L        1279.960       1221.406
                             AIC             1279.960       1227.406
                             SBC             1279.960       1235.891


                             Testing Global Null Hypothesis: BETA=0

                     Test                 Chi-Square       DF     Pr > ChiSq

                     Likelihood Ratio        58.5540        3         <.0001
                     Score                   58.2414        3         <.0001
                     Wald                    53.1118        3         <.0001


                                         The SAS System            08:47 Monday, May 12, 2008   2

                                       The PHREG Procedure

                            Analysis of Maximum Likelihood Estimates

                           Parameter      Standard                                  Hazard
       Parameter    DF      Estimate         Error    Chi-Square    Pr > ChiSq       Ratio

       age           1       0.03743       0.00889       17.7358        <.0001       1.038
       hepa          1       1.37558       0.35940       14.6490        0.0001       3.957
       hepat         1    -0.0001393     0.0001810        0.5927        0.4414       1.000
                                         The SAS System            08:47 Monday, May 12, 2008   3
                             Stratified Cox Regression for PBC data

                                       The PHREG Procedure

                                        Model Information

                                Data Set                 WORK.A
                                Dependent Variable       time
                                Censoring Variable       delta
                                Censoring Value(s)       0
                                Ties Handling            BRESLOW


                             Number of Observations Read         312
                             Number of Observations Used         312


                        Summary of the Number of Event and Censored Values

                                                                           Percent
               Stratum    hepa           Total       Event    Censored    Censored

                     1    0                152          37         115       75.66
                     2    1                160          88          72       45.00
               -------------------------------------------------------------------
                 Total                     312         125         187       59.94


                                       Convergence Status

                         Convergence criterion (GCONV=1E-8) satisfied.


                                      Model Fit Statistics

                                              Without           With
                             Criterion     Covariates     Covariates

                             -2 LOG L        1095.187       1077.452
                             AIC             1095.187       1079.452
                             SBC             1095.187       1082.281


                             Testing Global Null Hypothesis: BETA=0

                     Test                 Chi-Square       DF     Pr > ChiSq

                     Likelihood Ratio        17.7345        1         <.0001
                     Score                   17.8981        1         <.0001
                     Wald                    17.7331        1         <.0001


                                         The SAS System            08:47 Monday, May 12, 2008   4
                             Stratified Cox Regression for PBC data

                                       The PHREG Procedure

                            Analysis of Maximum Likelihood Estimates

                           Parameter      Standard                                  Hazard
       Parameter    DF      Estimate         Error    Chi-Square    Pr > ChiSq       Ratio

       age           1       0.03745       0.00889       17.7331        <.0001       1.038