The SAS System 09:33 Monday, May 12, 2008 1 The CONTENTS Procedure Data Set Name WORK.A Observations 1571 Member Type DATA Variables 23 Engine V9 Indexes 0 Created Monday, May 12, Observation Length 184 2008 09:34:06 AM Last Modified Monday, May 12, Deleted Observations 0 2008 09:34:06 AM Protection Compressed NO Data Set Type Sorted NO Label Data Representation WINDOWS_32 Encoding wlatin1 Western (Windows) Engine/Host Dependent Information Data Set Page Size 16384 Number of Data Set Pages 19 First Data Page 1 Max Obs per Page 88 Obs in First Data Page 71 Number of Data Set Repairs 0 Filename C:\DOCUME~1\cai\LOCALS~1\Temp\SAS Temporary Files\_TD3536\a.sas7bdat Release Created 9.0201M0 Host Created XP_PRO Alphabetic List of Variables and Attributes # Variable Type Len 3 age45 Num 8 12 agechd Num 8 15 agechf Num 8 17 agecva Num 8 20 aged Num 8 2 agev1 Num 8 22 blood Num 8 4 bmi45 Num 8 5 chol45 Num 8 7 dbp45 Num 8 11 deltachd Num 8 13 deltachdd Num 8 14 deltachf Num 8 16 deltacva Num 8 18 deltacvad Num 8 19 deltad Num 8 8 hbp Num 8 1 id Num 8 6 sbp45 Num 8 The SAS System 09:33 Monday, May 12, 2008 2 The CONTENTS Procedure Alphabetic List of Variables and Attributes # Variable Type Len 10 sex Num 8 9 smoke Num 8 23 unit Num 8 21 wait Num 8 The SAS System 09:33 Monday, May 12, 2008 3 d e c l a a b h s d s t g g m o b b m a O e e i l p p h o s c b i v 4 4 4 4 4 b k e h s d 1 5 5 5 5 5 p e x d 1 3 41.833 44.167 31.116 181 121.333 81.333 0 0 1 0 2 6 39.083 44.333 24.418 220 107.500 67.500 0 0 1 0 3 8 42.250 45.417 25.824 281 121.333 82.667 0 1 0 0 4 10 36.333 44.417 23.119 234 111.000 70.000 0 1 1 0 5 12 35.833 45.750 26.405 232 105.000 57.000 0 1 0 0 6 14 39.500 45.500 28.730 307 110.000 78.000 0 1 0 0 7 22 37.250 45.333 23.172 195 108.000 74.667 0 1 1 0 8 25 40.167 44.917 24.829 208 116.000 71.000 0 1 0 0 9 31 37.250 45.333 24.301 228 111.333 74.667 0 1 1 0 10 34 36.000 45.583 21.106 182 132.000 77.333 1 0 1 0 11 37 35.833 45.750 19.207 178 110.000 70.000 0 0 1 0 12 40 40.500 44.750 27.118 334 122.000 83.667 0 0 0 1 13 41 41.583 44.250 23.232 194 108.667 63.333 0 0 1 0 14 45 40.583 44.833 28.553 242 110.667 67.000 0 1 0 1 15 47 41.750 44.917 20.302 267 102.667 74.667 0 1 1 0 16 48 39.083 45.083 23.539 271 121.000 77.000 0 0 1 0 d d e d d e l e e l a t l a l a t d g a t g t g a e b e c a e a e c l a w l u O c h c c c c v t g a o n b h d h h v v a a e i o i s d d f f a a d d d t d t 1 54.417 0 2 54.417 0 54.417 0 1 54.417 2.485 2 2 2 69.750 0 2 69.750 1 64.917 0 0 69.750 5.345 4 4 3 71.083 0 2 71.083 0 71.083 0 0 71.083 3.312 5 5 4 67.000 0 2 67.000 0 67.000 0 0 67.000 8.238 7 7 5 66.583 0 2 66.583 0 66.583 0 0 66.583 10.011 9 8 6 70.250 0 2 70.250 0 70.250 0 0 70.250 6.159 11 10 7 68.083 0 2 68.083 0 68.083 0 0 68.083 8.208 16 15 8 70.917 0 2 70.917 0 70.917 0 0 70.917 4.855 17 16 9 68.000 0 2 68.000 0 68.000 0 0 68.000 8.178 21 20 10 62.583 0 2 62.583 0 62.583 0 0 62.583 9.690 24 23 11 67.583 0 2 67.583 0 67.583 0 0 67.583 10.014 26 25 12 68.333 0 2 71.250 0 71.250 0 0 71.250 4.362 29 27 13 72.333 0 2 72.333 0 72.333 0 0 72.333 2.816 30 16 14 68.167 0 2 71.417 0 71.417 0 0 71.417 4.353 32 29 15 70.583 0 2 70.583 1 68.000 0 0 70.583 3.266 33 5 16 69.833 0 2 69.833 0 69.833 0 0 69.833 6.093 34 30 The SAS System 09:33 Monday, May 12, 2008 4 d e c l a a b h s d s t g g m o b b m a O e e i l p p h o s c b i v 4 4 4 4 4 b k e h s d 1 5 5 5 5 5 p e x d 17 51 41.500 44.667 22.284 209 138.000 89.333 1 0 0 0 18 63 39.583 45.583 22.317 185 139.000 87.000 1 0 1 0 19 65 38.667 44.667 23.405 220 112.000 70.000 0 0 1 0 20 68 40.667 45.833 23.503 220 121.000 74.500 0 0 1 0 d d e d d e l e e l a t l a l a t d g a t g t g a e b e c a e a e c l a w l u O c h c c c c v t g a o n b h d h h v v a a e i o i s d d f f a a d d d t d t 17 72.167 0 2 72.167 0 72.167 0 0 72.167 3.279 36 4 18 66.500 0 2 66.500 0 66.500 0 0 66.500 6.110 44 38 19 69.417 0 2 69.417 0 69.417 0 0 69.417 6.110 46 40 20 56.750 0 2 56.750 0 56.750 0 0 56.750 5.323 48 42 The SAS System 09:33 Monday, May 12, 2008 5 The FREQ Procedure Cumulative Cumulative deltachd Frequency Percent Frequency Percent ƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒ 0 1321 84.09 1321 84.09 1 250 15.91 1571 100.00 Cumulative Cumulative deltacva Frequency Percent Frequency Percent ƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒƒ 0 1520 96.75 1520 96.75 1 51 3.25 1571 100.00 Table of deltachd by deltacva deltachd deltacva Frequency‚ Percent ‚ Row Pct ‚ Col Pct ‚ 0‚ 1‚ Total ƒƒƒƒƒƒƒƒƒˆƒƒƒƒƒƒƒƒˆƒƒƒƒƒƒƒƒˆ 0 ‚ 1287 ‚ 34 ‚ 1321 ‚ 81.92 ‚ 2.16 ‚ 84.09 ‚ 97.43 ‚ 2.57 ‚ ‚ 84.67 ‚ 66.67 ‚ ƒƒƒƒƒƒƒƒƒˆƒƒƒƒƒƒƒƒˆƒƒƒƒƒƒƒƒˆ 1 ‚ 233 ‚ 17 ‚ 250 ‚ 14.83 ‚ 1.08 ‚ 15.91 ‚ 93.20 ‚ 6.80 ‚ ‚ 15.33 ‚ 33.33 ‚ ƒƒƒƒƒƒƒƒƒˆƒƒƒƒƒƒƒƒˆƒƒƒƒƒƒƒƒˆ Total 1520 51 1571 96.75 3.25 100.00 The SAS System 09:33 Monday, May 12, 2008 6 Obs id age45 bmi45 chol45 sbp45 smoke sex wait time status disease 1 3 44.167 31.116 181 121.333 0 1 2.485 10.250 0 1 2 3 44.167 31.116 181 121.333 0 1 2.485 10.250 0 2 3 6 44.333 24.418 220 107.500 0 1 5.345 25.417 0 1 4 6 44.333 24.418 220 107.500 0 1 5.345 20.584 1 2 5 8 45.417 25.824 281 121.333 1 0 3.312 25.666 0 1 6 8 45.417 25.824 281 121.333 1 0 3.312 25.666 0 2 7 10 44.417 23.119 234 111.000 1 1 8.238 22.583 0 1 8 10 44.417 23.119 234 111.000 1 1 8.238 22.583 0 2 9 12 45.750 26.405 232 105.000 1 0 10.011 20.833 0 1 10 12 45.750 26.405 232 105.000 1 0 10.011 20.833 0 2 The SAS System 09:33 Monday, May 12, 2008 7 The PHREG Procedure Model Information Data Set WORK.DATA_CHD Dependent Variable time Censoring Variable status Censoring Value(s) 0 Ties Handling BRESLOW Number of Observations Read 1571 Number of Observations Used 1571 Summary of the Number of Event and Censored Values Percent Total Event Censored Censored 1571 250 1321 84.09 Convergence Status Convergence criterion (GCONV=1E-8) satisfied. Model Fit Statistics Without With Criterion Covariates Covariates -2 LOG L 3447.815 3433.180 AIC 3447.815 3439.180 SBC 3447.815 3449.745 Testing Global Null Hypothesis: BETA=0 Test Chi-Square DF Pr > ChiSq Likelihood Ratio 14.6343 3 0.0022 Score 15.3142 3 0.0016 Wald 15.3879 3 0.0015 The SAS System 09:33 Monday, May 12, 2008 8 The PHREG Procedure Analysis of Maximum Likelihood Estimates Parameter Standard Hazard Parameter DF Estimate Error Chi-Square Pr > ChiSq Ratio age45 1 0.18955 0.11368 2.7799 0.0955 1.209 bmi45 1 0.05768 0.01631 12.4997 0.0004 1.059 wait 1 0.00454 0.01850 0.0603 0.8060 1.005 The SAS System 09:33 Monday, May 12, 2008 9 The PHREG Procedure Model Information Data Set WORK.DATA_CVA Dependent Variable time Censoring Variable status Censoring Value(s) 0 Ties Handling BRESLOW Number of Observations Read 1571 Number of Observations Used 1571 Summary of the Number of Event and Censored Values Percent Total Event Censored Censored 1571 51 1520 96.75 Convergence Status Convergence criterion (GCONV=1E-8) satisfied. Model Fit Statistics Without With Criterion Covariates Covariates -2 LOG L 708.925 704.526 AIC 708.925 710.526 SBC 708.925 716.322 Testing Global Null Hypothesis: BETA=0 Test Chi-Square DF Pr > ChiSq Likelihood Ratio 4.3989 3 0.2215 Score 4.6738 3 0.1973 Wald 4.7234 3 0.1932 The SAS System 09:33 Monday, May 12, 2008 10 The PHREG Procedure Analysis of Maximum Likelihood Estimates Parameter Standard Hazard Parameter DF Estimate Error Chi-Square Pr > ChiSq Ratio age45 1 0.06738 0.25198 0.0715 0.7892 1.070 bmi45 1 0.07222 0.03564 4.1068 0.0427 1.075 wait 1 0.02768 0.04142 0.4466 0.5039 1.028 The SAS System 09:33 Monday, May 12, 2008 11 The PHREG Procedure Model Information Data Set WORK.COMBINED Dependent Variable time Censoring Variable status Censoring Value(s) 0 Ties Handling BRESLOW Number of Observations Read 3142 Number of Observations Used 3142 Summary of the Number of Event and Censored Values Percent Stratum disease Total Event Censored Censored 1 1 1571 250 1321 84.09 2 2 1571 51 1520 96.75 ------------------------------------------------------------------- Total 3142 301 2841 90.42 Convergence Status Convergence criterion (GCONV=1E-8) satisfied. Model Fit Statistics Without With Criterion Covariates Covariates -2 LOG L 4156.740 4137.707 AIC 4156.740 4149.707 SBC 4156.740 4171.949 Testing Global Null Hypothesis: BETA=0 Test Chi-Square DF Pr > ChiSq Likelihood Ratio 19.0332 6 0.0041 Score (Model-Based) 19.9880 6 0.0028 Score (Sandwich) 18.3664 6 0.0054 Wald (Model-Based) 20.1268 6 0.0026 Wald (Sandwich) 21.4564 6 0.0015 The SAS System 09:33 Monday, May 12, 2008 12 The PHREG Procedure Analysis of Maximum Likelihood Estimates Parameter Standard StdErr Hazard Parameter DF Estimate Error Ratio Chi-Square Pr > ChiSq Ratio age45chd 1 0.18955 0.11299 0.994 2.8141 0.0934 1.209 age45cva 1 0.06739 0.26374 1.047 0.0653 0.7983 1.070 bmi45chd 1 0.05768 0.01490 0.914 14.9771 0.0001 1.059 bmi45cva 1 0.07233 0.03258 0.914 4.9284 0.0264 1.075 waitchd 1 0.00454 0.01916 1.035 0.0562 0.8125 1.005 waitcva 1 0.02769 0.04410 1.065 0.3942 0.5301 1.028 The SAS System 09:33 Monday, May 12, 2008 13 The PHREG Procedure Linear Coefficients for Test age Average Parameter Row 1 Effect age45chd 1 0.87694 age45cva -1 0.12306 bmi45chd 0 0.00000 bmi45cva 0 0.00000 waitchd 0 0.00000 waitcva 0 0.00000 CONSTANT 0 0.00000 Test age Results Wald Chi-Square DF Pr > ChiSq 0.1981 1 0.6563 Average Effect for Test age Standard Estimate Error z-Score Pr > |z| 0.1745 0.1078 1.6185 0.1056 The SAS System 09:33 Monday, May 12, 2008 14 The PHREG Procedure Model Information Data Set WORK.COMBINED Dependent Variable time Censoring Variable status Censoring Value(s) 0 Ties Handling BRESLOW Number of Observations Read 3142 Number of Observations Used 3142 Summary of the Number of Event and Censored Values Percent Stratum disease Total Event Censored Censored 1 1 1571 250 1321 84.09 2 2 1571 51 1520 96.75 ------------------------------------------------------------------- Total 3142 301 2841 90.42 Convergence Status Convergence criterion (GCONV=1E-8) satisfied. Model Fit Statistics Without With Criterion Covariates Covariates -2 LOG L 4156.740 4137.902 AIC 4156.740 4147.902 SBC 4156.740 4166.438 Testing Global Null Hypothesis: BETA=0 Test Chi-Square DF Pr > ChiSq Likelihood Ratio 18.8377 5 0.0021 Score (Model-Based) 19.7926 5 0.0014 Score (Sandwich) 17.4319 5 0.0037 Wald (Model-Based) 19.9365 5 0.0013 Wald (Sandwich) 20.4196 5 0.0010 The SAS System 09:33 Monday, May 12, 2008 15 The PHREG Procedure Analysis of Maximum Likelihood Estimates Parameter Standard StdErr Hazard Parameter DF Estimate Error Ratio Chi-Square Pr > ChiSq Ratio age45 1 0.16886 0.10851 1.047 2.4217 0.1197 1.184 bmi45chd 1 0.05765 0.01491 0.914 14.9547 0.0001 1.059 bmi45cva 1 0.07247 0.03252 0.913 4.9655 0.0259 1.075 waitchd 1 0.00473 0.01914 1.035 0.0612 0.8047 1.005 waitcva 1 0.02673 0.04415 1.069 0.3665 0.5449 1.027 The SAS System 09:33 Monday, May 12, 2008 16 The PHREG Procedure Linear Coefficients for Test bmi_equal Average Parameter Row 1 Effect age45 0 0.00000 bmi45chd 1 0.86997 bmi45cva -1 0.13003 waitchd 0 0.00000 waitcva 0 0.00000 CONSTANT 0 0.00000 Test bmi_equal Results Wald Chi-Square DF Pr > ChiSq 0.1945 1 0.6592 Average Effect for Test bmi_equal Standard Estimate Error z-Score Pr > |z| 0.0596 0.0143 4.1800 <.0001 The SAS System 09:33 Monday, May 12, 2008 17 The PHREG Procedure Linear Coefficients for Test bmi Average Parameter Row 1 Row 2 Effect age45 0 0 0.00000 bmi45chd 1 0 0.86997 bmi45cva 0 1 0.13003 waitchd 0 0 0.00000 waitcva 0 0 0.00000 CONSTANT 0 0 0.00000 Test bmi Results Wald Chi-Square DF Pr > ChiSq 17.6666 2 0.0001 Average Effect for Test bmi Standard Estimate Error z-Score Pr > |z| 0.0596 0.0143 4.1800 <.0001