BIOS 280 Survival Analysis Homework 2 2/1/1996 Read: K&P, chapters 4, 5. Cox (1972) JRSS, p 187. Cox (1975) Biometrika (Partial Likelihood) p 269. 1. Suppose T_1, ..., T_n are i.i.d from a Weibull distribution with parameters \lambda=1, \kappa=2; H(t) = (\lambda t)^\kappa. We wish to estimate S(0.8325546112), which happens to be 0.5. Note: There is no censoring. Consider two estimators: (i) One based on the empirical distribution function. (ii) One based on fitting an exponential model, which is the wrong model. Large sample theory tells us that the second estimator is not consistent. Tabulate the root mean square error (RMSE) for each estimator for sample sizes n=1, 5, 10, 15, 20, 25. Use simulation approximation if exact quantities are difficult to compute. Present a table showing bias, variance and RMSE for each n. Comment. 2. K&P, #15 (page 243).